Dr. Daniel P. Sipple | Blaine Physical Medicine Physician | Midwest Spine & Brain Institute
Spine Care
Daniel P. Sipple D.O., F.A.B.P.M.R.,  D.A.B.P.M.

Daniel P. Sipple D.O., F.A.B.P.M.R., D.A.B.P.M.

Practice Locations

Daniel P. Sipple D.O., F.A.B.P.M.R.,  D.A.B.P.M.

Dr. Daniel Sipple is an expert in conservative management of a variety of spinal, musculoskeletal, and pain conditions. He is double board certified in physical medicine and rehabilitation and pain medicine. His practice focuses on the use of minimally invasive treatments such as ultrasound guided interventions, radiofrequency ablation, spinal cord stimulation, physical modalities, epidural injections to alleviate pain, restore function and quality of life.

In addition to technical expertise with several thousand procedures performed, Dr. Sipple is known to address the whole person in the context of a clinical relationship. Physiatry, or physical medicine and rehabilitation, is the bridge between primary care and surgery for patients with spinal, pain and musculoskeletal conditions. Sleep, bone density, biomechanics, stress, sexual dysfunction and other health factors impact patient’s outcomes and quality of life. By addressing such factors, both surgical and non-surgical outcomes are enhanced.

Dr. Sipple counts himself fortunate to have trained at the Rehabilitation Institute of Chicago (RIC), rated by US News and World Report as the #1 hospital in its field for over 20 consecutive years, the only hospital in the country with such a distinction. After serving on faculty at Northwestern University Medical School at RIC’s pain center, an AAPM nationally recognized center of excellence, he pursued fellowship training with Dr. Michael B Furman. Subsequently, he worked in orthopedics in Denver followed by anesthesia interventional pain practice with Dr. Steven Endres. There, Dr. Sipple participated in Dr. Endres’ research that changed the guidelines for use of anti-coagulation for spinal interventions internationally. He successfully lead the turnaround of the HealthEast Spine Center as Medical Director and Service Line Medical Director before returning to private practice with MSBI.

Taking after his father, an electrical engineer, Dr. Sipple enjoys being on the cutting edge of device and medication development, being a patent holder of smart needle technology and a co-founder of InSitu Biolgics. He is sought after for interventional skills in radiofrequency ablation, spinal cord stimulation, discography and expert witness testimony.

A Minnesota native, Dr. Sipple is thankful for the loving support of his family, along with agrarian work ethic they helped instill. Dr. Sipple funded his college education working summers at Pepsi-Cola. His down to earth approach relates to the needs of injured workers. He is often found with his daughter, yellow lab, smoking chicken, fishing and downhill skiing, when not at work.

It is Dr. Sipple’s philosophy that in many cases Coumadin, Plavix and other blood thinners need not be stopped prior to routine lumbar spinal procedures. This greatly reduces the risk of stroke and heart attack. He performs full spectrum spinal pain interventions including epidural steroid injections, sacroiliac joint injections, radiofrequency ablation, spinal cord stimulation, discography and ultrasound guided tenotomy.



University of Minnesota, Twin Cities - B.A., Phi Beta Kappa

Medical School:

Des Moines University-Osteopathic Medical Center


University of Massachusetts


Rehabilitation Institute of Chicago/Northwestern University
Physical Medicine & Rehabilitation


Sinai Hospital of Baltimore/ Orthopedic & Spine Specialists of York, PA.
Interventional Pain Fellowship

Professional Experience


Midwest Spine & Brain Institute, LLC.
HealthEast: Service Line Medical Director: Brain, Pain & Spine
InSitu Biologics, Founder, Board & Medical Advisor,
Pain Clinic of Northwestern Wisconsin, Eau Claire, WI
Advanced Orthopedics and Sports Medicine Specialists, Denver, CO
Rehabilitation Institute of Chicago, Northwestern University Faculty



Board Certified American Board of Physical Medicine and Rehabilitation
Subspecialty Board Certification in Pain Management



Professional Memberships and Services

  • The American Academy of Physical Medicine and Rehabilitation
  • International Spine Intervention Society
  • American Institute of Ultrasound in Medicine


U.S. Provisional Patent Application 62/014,513, June 2014
Biomarker Detection and Identification System and Apparatus

Sipple D, Hudgins T. “Foot and Ankle Bursitis” in Silver, Frontera. Essentials of
Physical Medicine and Rehabilitation, 2nd Edition, May 2008

Plastaras C, Marciniak CM, Sipple D. The effect of Interelectrode Distance on Sural
Nerve Action Potential Parameters. Am J Phys Med Rehabil. 2008 Mar; 87(3):183-188

Sipple D, Philip P. Bitemporal hemianopsia: A rare complication of severe traumatic
brain injury- A case report and review of mechanism of injury Archives Physical
Medicine & Rehabilitation, Volume 87, Issue 11, Pg e7. Presented at the
Annual Assembly of the AAPM&R, Honolulu, Hawaii, November 2006.

Sipple, D. Lou Gehrig’s Disease: A Case Report and Review of the Literature
J POMA, 46 (3): 18-21, 2002.

Guiang S, Sipple D, Georgieff MK. Chronic Neonatal Hypoxemia Increases Cardiac Myoglobin and is Associated with Preservation of In Vitro Myocardial Contractility in
Iron Deficient Guinea Pigs. Pediatric Research, 45 (4): 1668. 1999 [Abstract]